Answer of Dermatopathology Case 73
Histochemistry : Methenamine silver stain shows Histoplasma capsulatum fungi. Cutaneous Histoplasmosis Visit: Dermatopathology site Visit : Pathology of Histoplasmosis Abstract: Histoplasmosis Presenting as a Cutaneous Malignancy of the Eyelid. Ophthal Plast Reconstr Surg. 2010 Sep 20. Cutaneous histoplasmosis is an uncommon infection and can occur as a primary infection. A manifestation imitating a cutaneous neoplasm is rare, and eyelid involvement is rarer still. The authors report a case of histoplasmosis that presented as an ulcerated lesion on the lower eyelid margin that clinically resembled a basal cell carcinoma. Given its worldwide distribution, it is important to include this disease in the differential diagnosis of nonhealing eyelid lesions. Biopsy and tissue culture are paramount to establishing the diagnosis. This case describes a rare presentation of histoplasmosis on the eyelid and highlights the importance of histopathologic evaluation. Primary Cutaneous Histoplasmosis
