Dermatopathology Case 200

25 year-old female who presented with a  9 month history of a left foot mass. It started as a small nodule that progressively increased in size over time. The mass then became ulcerative with foul-smelling discharge.

Immunohistochemistry- Positive against the following markers: S-100, HMB45, Melan A, and Bcl2

Negative staining for cytokeratin, epithelial membrane antigen, smooth muscle actin , Desmin, CD34, CD56, Myogenin, and CD57 markers was also observed.

 


 


 


 


 


 


 


 


 


 

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