Answer of Dermatopathology Case 15
Cylindroma Visit: Pathology of Cylindroma Visit: Dermatopathology site Abstract: Cylindroma of the breast: a case report and review of the literature. Diagn Pathol. 2009 Sep 2;4:30. ABSTRACT: Cylindroma of the breast is a very rare lesion which is morphologicaland immunophenotypically identical to benign dermal cylindroma. We report a breast cylindroma in a previously healthy 62 year old female detected through anational breast screening program. The patient had no significant family or past medical history, and specifically no history of breast or skin diseases. The tumor consisted of well circumscribed islands of epithelial cells surrounded by adense membrane material, and focally containing hyaline globules. At low power the islands of tumour cells formed a "jig-saw" pattern, which is typical of cylindroma, but was present within normal breast parenchyma and no had directconnection with the overlying skin. Two distinct cell populations, smaller peripheral basaloid cells an